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. Author manuscript; available in PMC: 2014 May 1.

Published in final edited form as: Pediatr Crit Care Med. 2013 May;14(4):374–383. doi: 10.1097/PCC.0b013e318274568c

Top Left Panel: Freedom from nosocomial sepsis according to assigned treatment for patients immunocompetent at study entry, using data available at time of second interim analysis. Numbers above the horizontal time axis denote number of patients remaining at risk at each timepoint. Top Right Panel: Freedom from nosocomial sepsis according to assigned treatment for patients immunocompromised at study entry, using data available at time of second interim analysis. Numbers above the horizontal time axis denote number of patients remaining at risk at each timepoint. Bottom Left Panel: Freedom from nosocomial sepsis according to assigned treatment for female patients, using data available at time of second interim analysis. Numbers above the horizontal time axis denote number of patients remaining at risk at each timepoint. Bottom Right Panel: Freedom from nosocomial sepsis according to assigned treatment for male patients, using data available at time of second interim analysis. Numbers above the horizontal time axis denote number of patients remaining at risk at each timepoint.

Top Left Panel: Freedom from nosocomial sepsis according to assigned treatment for patients immunocompetent at study entry, using data available at time of second interim analysis. Numbers above the horizontal time axis denote number of patients remaining at risk at each timepoint. Top Right Panel: Freedom from nosocomial sepsis according to assigned treatment for patients immunocompromised at study entry, using data available at time of second interim analysis. Numbers above the horizontal time axis denote number of patients remaining at risk at each timepoint. Bottom Left Panel: Freedom from nosocomial sepsis according to assigned treatment for female patients, using data available at time of second interim analysis. Numbers above the horizontal time axis denote number of patients remaining at risk at each timepoint. Bottom Right Panel: Freedom from nosocomial sepsis according to assigned treatment for male patients, using data available at time of second interim analysis. Numbers above the horizontal time axis denote number of patients remaining at risk at each timepoint.