Table 3.
Whole-Brain Correlations with Steroid Levels
| Steroid (pg/ml) and Brain Region | Cluster Size | MNI coordinates (x,y,z) | Analysis (r) |
|---|---|---|---|
| Pregnenolone | |||
| Right Insula | 12 | 42, 11, 4 | −.65 |
| Right Inferior Frontal Gyrus | 12 | 48, 11, 37 | −.62 |
| Allopregnanolone | |||
| Right Amygdala | 10 | 27, −1, −17 | −.66 |
| Pregnanolone | |||
| Right Lingual Gyrus | 18 | 33, −70, 7 | .62 |
| Right Insula | 127 | 30, 8, 7 | −.68 |
| Medial Frontal Gyrus | 11 | 18, 38, 31 | −.56 |
*
Correlations were conducted with change scores (natural log transformed steroid levels at endpoint minus baseline), and are significant at p<.001, uncorrected, extent threshold k>10.