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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Expert Opin Drug Deliv. 2013 Jan 25;10(4):499–509. doi: 10.1517/17425247.2013.764864

Table 1.

Hydrogels for Lentiviral Delivery

Hydrogel Material Strategy for Enhanced Transduction Application Reference
Collagen Hydroxyapatite nanoparticles (non-specific vector retention) Subcutaneous implant [37]
Collagen Encapsulation only In vitro cell culture [48]
Fibrin Encapsulation only In vitro cell microarrays [35,70]
Fibrin Hydroxyapatite nanoparticles (non-specific vector retention) Subcutaneous implant [39]
Fibrin Fusion peptide/VSV-G envelope (conjugation to vector) In vitro cell microarrays [45]
Chitosan/β-Glycerol Positive charge on chitosan (non-specific vector retention) In vitro cell culture [46]
Phosphate blend
PEG Encapsulation only 3D stem cell culture [44]
PEG/Gelatin Macropores (increased cell infiltration) Subcutaneous gene transfer [40]