Table 1.
Hydrogel Material | Strategy for Enhanced Transduction | Application | Reference |
---|---|---|---|
Collagen | Hydroxyapatite nanoparticles (non-specific vector retention) | Subcutaneous implant | [37] |
Collagen | Encapsulation only | In vitro cell culture | [48] |
Fibrin | Encapsulation only | In vitro cell microarrays | [35,70] |
Fibrin | Hydroxyapatite nanoparticles (non-specific vector retention) | Subcutaneous implant | [39] |
Fibrin | Fusion peptide/VSV-G envelope (conjugation to vector) | In vitro cell microarrays | [45] |
Chitosan/β-Glycerol | Positive charge on chitosan (non-specific vector retention) | In vitro cell culture | [46] |
Phosphate blend | |||
PEG | Encapsulation only | 3D stem cell culture | [44] |
PEG/Gelatin | Macropores (increased cell infiltration) | Subcutaneous gene transfer | [40] |