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A) Schematic representation of the plasmids used to generate a stable transgenic fish expressing Gal4-VP16 in motor neurons under the mnx1 promoter, and the vectors used for expressing N-cadherin cytoplasmic domain fused to the IL2α subunit receptor (IL2α-cdh2-CD & pren-EGFP) and IL2α C-terminally fused to EGFP (IL2α-EGFP). B) Schematic representation of full length N-cadherin and domain-deleted constructs used as dominant-interfering proteins. ED, ectodomain; CD, cytoplasmic domain.
