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. 2013 Apr 27;5(4):206–213. doi: 10.4254/wjh.v5.i4.206

Figure 2.

Figure 2

Quantitation of hepatocyte nuclear apurinic/apyrimidinic endonuclease 1 protein immunostaining. A: The percentage of positive hepatocellular nuclei throughout the slide was consistently 80%-100%, regardless of the etiology of chronic liver disease, while the staining intensity was lower in hepatitis B virus (HBV) group than in hepatitis C virus (HCV), autoimmune hepatitis (AIH)/primary biliary cirrhosis (PBC) and normal groups (aP < 0.05 vs HCV, dP < 0.01 vs AIH/PBC, eP < 0.05 vs normal); B: The staining intensity of hepatocytic nuclear apurinic/apyrimidinic endonuclease 1 (APE-1) protein was positively correlated with serum alanine aminotransferase (ALT) levels in the HBV (r = 0.42, P < 0.05) and HCV groups (r = 0.38, P < 0.05).