Table 1.
Clinical characteristics in patients with chronic liver disease
| Characteristics | HCV (n = 30) | HBV (n = 27) | AIH (n = 6) | PBC (n = 6) | HCV vs HBV |
| Gender (male/female) | 18/12 | 18/9 | 0/6 | 1/5 | NS |
| Age (yr) | 56.8 ± 9.1 (39-73) | 52.6 ± 12.9 (22-69) | 58.5 ± 12.2 (47-74) | 56.3 ± 7.0 (44-64) | NS |
| Platelet count (× 104/mm3) | 15.7 ± 5.9 (9.3-32.3) | 14.6 ± 6.2 (8.2-28.4) | 14.9 ± 7.6 (12.7-26.0) | 16.0 ± 4.4 (13.4-23.6) | NS |
| AST (IU/L) | 55 ± 36 (13-191) | 135 ± 84 (59-341) | 118 ± 32 (47-120) | 32 ± 6 (21-35) | P < 0.001 |
| ALT (IU/L) | 71 ± 60 (16-307) | 180 ± 153 (79-554) | 138 ± 37 (54-144) | 45 ± 18 (11-53) | P < 0.001 |
| γGTP (IU/L) | 45 ± 36 (14-175) | 84 ± 43 (41-135) | 147 ± 53 (35-228) | 114 ± 63 (23-179) | P < 0.01 |
| Viral load | > 500 KIU/mL (n = 16) | ||||
| 100-500 KIU/mL (n = 4) | > 7.6 log copies/mL (n = 11) | ||||
| < 100 KIU/mL (n = 10) | ≤ 7.6 log copies/mL (n = 16) | ||||
| Liver histopathology | Ludwig’s stage | ||||
| Necroinflammation (mild/moderate/severe) | 5/20/5 | 7/15/5 | 2/3/1 | Portal stage (n = 2) | NS |
| Periportal stage (n = 4) | |||||
| Fibrosis (none/mild/moderate/severe/cirrhosis) | 0/17/8/4/1 | 3/10/8/4/2 | 1/4/1/0/0 | Septal stage (n = 0) | |
| Cirrhotic stage (n = 0) | NS |
Values represent mean ± SE unless otherwise stated. HCV: Hepatitis C virus; HBV: Hepatitis B virus; AIH: Autoimmune hepatitis; PBC: Primary biliary cirrhosis; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; γGTP: γ glutamyl transpeptidase.