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. Author manuscript; available in PMC: 2013 May 9.
Published in final edited form as: Nat Med. 2007 Feb 4;13(2):189–197. doi: 10.1038/nm1545

Figure 1. Aldosterone decreases G6pd expression and activity.

Figure 1

BAEC were treated with aldosterone (ALDO) or vehicle (V) for 24 h and the effect of ALDO on (a) mineralocorticoid receptor (MR) expression, (b) G6pd protein expression, and G6pd mRNA levels by (c) Northern blotting and (d) quantitative real-time PCR (n=4) was assessed. Concomitant changes in (e) G6PD activity (n = 8) and (f) NADPH levels (n = 4) were determined (* P < 0.01 vs. V, ** P <0.001 vs. V). Representative blots are shown and densitometry was performed on a minimum of three blots and reported as arbitrary units (a.u.). Data represent mean ± SEM.