Table 3.
Hamster No. | SV40 strain inoculated | Sacrificed (months p.i.) | Cell line designationa | Virus production (passage no.)b | Viral genomes per cell (passage no.)b | Ratio of early to late SV40 mRNA (passage no.)b | T-antigen expression |
---|---|---|---|---|---|---|---|
1087 | VA45-54(2E) | 6 | S1087 | No (P2) | 4 (P6) | 55 (P31) | Yes |
1109 | 776-VA(2E) | 6 | S1109 | No (P2) | 7 (P4) | 43 (P31) | Yes |
1113 | 776-VA(2E) | 8 | S1113 | No (P2) | 6 (P1) | 15 (P33) | Yes |
Cell lines established from enlarged spleens of hamsters.
Passage no., passage level of the cell line tested.