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. Author manuscript; available in PMC: 2013 May 9.
Published in final edited form as: Psychopharmacology (Berl). 2012 Mar 13;226(4):687–698. doi: 10.1007/s00213-012-2681-5

Fig. 2.

Fig. 2

Neither VTA orexin nor ionotropic glutamate transmission is necessary for cocaine-primed reinstatement. Extinction (left bar): the average of the last 2 days of extinction responding immediately before reinstatement tests is shown for comparison with cocaine-primed reinstatement. Systemic SB injection: cocaine-primed reinstatement behavior is shown after systemic injections of vehicle or SB-334867 (10 or 30 mg/kg, i.p.). VTA microinjection: cocaine-primed reinstatement behaviors are shown after bilateral intra-VTA SB (1mM) or CNQX/AP-5 (0.7/1.6 mM). Inactive lever presses on reinstatement test days are shown with black bars