Table I.

IpaB-Mediated Dextran Release from Phospholipid Vesicles

Dextran	Molecular weight (kDa)a	Hydrodynamic diameter (nm)b	Dextran release (%)c
D3-Fluorescein	1.5–2	2.1 ± 0.2	42.3 ± 3.4
D10-Fluorescein	9–11	2.3 ± 0.3	31.0 ± 2.8
D40-Fluorescein	35–50	3.2 ± 0.2	30.0 ± 1.2
D70-Fluorescein	60–90	5.5 ± 0.5	12.0 ± 0.2

^aMolecular weight range provided by the manufacturer.

^bHydrodynamic diameter determined by DLS. (n = 30 measurements spanning three independent samples).

^cRelease of fluorescent dextrans was monitored following introduction of 15 nM IpaB oligomer in 0.5% OPOE. Release was quantified as a percent of the total fluorescence following complete liposome lysis with Triton X-100. (n = 3 independent measurements).