Table 3.
Relationship between clinicopathological parameters in Nigerian and UK tumours expressing KI-67.
| Variables | KI-67 positive expression | |||
|---|---|---|---|---|
| Nigeria (%) | UK (%) | χ 2 value | P value | |
| Age (years) | ||||
| ≤50 | 136 (62.4) | 62 (37.8) | 22.65 | <0.001 |
| >50 | 82 (37.6) | 102 (62.2) | ||
| Menopausal | ||||
| Pre | 157 (72.0) | 60 (36.8) | 47.15 | <0.001 |
| Post | 61 (28.0) | 103 (63.2) | ||
| Sizes (cm) | ||||
| ≤2 | 18 (8.3) | 73 (44.5) | 67.79 | <0.001 |
| >2 | 200 (91.7) | 91 (55.5) | ||
| Lymph node involvement | ||||
| Negative | 16 (7.3) | 97 (59.1) | 120.58 | <0.001 |
| Positive | 202 (92.7) | 67 (40.9) | ||
| Vascular invasion | ||||
| Negative | 51 (23.4) | 86 (52.4) | 34.32 | <0.001 |
| Positive | 167 (76.6) | 78 (47.6) | ||
| Tumour type | ||||
| Typical medullary | 3 (1.4) | 1 (0.6) | 43.10 | <0.001 |
| Atypical medullary | 4 (1.8) | 7 (4.3) | ||
| Tubular | 1 (0.5) | 0 (0.0) | ||
| Lobular | 3 (1.4) | 8 (4.9) | ||
| Ductal NST | 189 (86.7) | 105 (64.8) | ||
| Mucinous | 4 (1.8) | 0 (0.0) | ||
| Tubulolobular | 0 (0.0) | 7 (4.3) | ||
| Mixed NST | 14 (6.4) | 30 (18.5) | ||
| Others | 0 (0.0) | 2 (1.2) | ||
NST: no special type. Others: metaplastic, spindle, and alveolar lobular histological type.