Table 2.
Clinical, demographic, and laboratory characteristics of HIV-HBV coinfection status groups.
| Characteristics | Hepatitis BsAg positive (HIV-HBV dually infected) |
Hepatitis BsAg negative | Missing data | P value |
|---|---|---|---|---|
| Mean age in years ± SD | 9.74 ± 4.08 | 7.34 ± 4.19 | 0.00 | |
| Age group in years | ||||
| ≤5 | 6 | 153 | 0.00 | |
| 6–10 | 8 | 114 | ||
| 11–15 | 17 | 97 | ||
|
| ||||
| Total | 31 | 364 | ||
|
| ||||
| Gender | ||||
| Male | 12 | 193 | 0.18 | |
| Female | 19 | 171 | ||
|
| ||||
| Total | 31 | 364 | ||
|
| ||||
| HBV immunization | ||||
| None/incomplete | 20 | 309 | 0.01 | |
| Complete | 11 | 55 | ||
|
| ||||
| Total | 31 | 364 | ||
|
| ||||
| Route of HIV acquisitions | ||||
| MTCT | 27 | 339 | 0.55 | |
| Blood transfusion | 1 | 6 | ||
| Others (sexual) | 0 | 2 | ||
| Unknown | 3 | 17 | ||
|
| ||||
| Total | 31 | 364 | ||
|
| ||||
| WHO staging* | ||||
| 1 and 2 | 21 | 250 | 0.91 | |
| 3 and 4 | 10 | 105 | ||
|
| ||||
| Total | 31 | 355 | ||
|
| ||||
| Absolute CD4 count in cells/mm, median (IQR)* | 334.00 (182.50–830.50) | 560.00 (275.00–916.80) | 108 | 0.11 |
| CD4%* | ||||
| <15 | 12 | 64 | 0.00 | |
| 15–25 | 2 | 50 | ||
| >25 | 6 | 144 | ||
|
| ||||
| Total | 20 | 258 | ||
|
| ||||
| Log10 viral load, Mean ± SD* | 4.26 ± 1.29 | 4.51 ± 1.17 | 118 | 0.33 |
| ALT, Median (IQR)* | 30.20 (18.50–50.70) | 24.70 (16.65–35.32) | 8 | 0.08 |
| Hepatotoxicity* | ||||
| Normal | 20 | 270 | 0.43 | |
| Elevated | 11 | 77 | ||
|
| ||||
| Total | 31 | 347 | ||
SD: standard deviation.
IQR: interquartile range.
*Data of 9 subjects (HIV-HCV coinfected) were excluded.