Skip to main content
. Author manuscript; available in PMC: 2013 Aug 21.
Published in final edited form as: Circulation. 2012 Jul 11;126(8):920–927. doi: 10.1161/CIRCULATIONAHA.111.076877

Table 3.

Adjusted hazard ratios (95% confidence intervals) for the association of physical and sexual abuse in childhood with risk of cardiovascular events in adulthood, Nurses’ Health Study 2, 1989–2007

Cases Person-Years Model 1:
Adjusted for age		 Model 2:
Adjusted for age and childhood covariates preceding abuse1 		Model 3:
Model 2 plus adult covariates2
Physical Abuse
None 226
537,165		 1.00 1.00 1.00
Mild 82
214,508		 0.91
0.71–1.18		 0.91
0.70–1.17		 0.87
0.68–1.13
Moderate 137
301,260		 1.06
0.85–1.31		 1.02
0.82–1.26		 0.93
0.74–1.15
Severe 68
97,860		 1.59
1.21–2.08		 1.46
1.11–1.92		 1.13
0.85–1.51
p-value3 0.006 0.03 0.40
Sexual Abuse
None 306
767,975		 1.00 1.00 1.00
Sexual touching 119
254,752		 1.13
0.91–1.40		 1.10
0.88–1.35		 1.02
0.82–1.27
Forced sex 88
128,066		 1.71
1.35–2.17		 1.56
1.23–1.99		 1.25
0.98–1.60
p-value3 0.0002 0.002 0.22
1

Model 2 is adjusted for age, race, age 5 somatotype, parental education, and parental MI or stroke

2

Model 3 is adjusted for variables in Model 2 plus: adult BMI, smoking, alcohol use, depression and intimate partner violence, quintiles of animal fat consumption, vegetable fat consumption, glycemic index in high school and updated throughout adulthood; oral contraceptive use; parity; menopausal status; postmenopausal hormone use; physical activity; incident hypertension and diabetes.

3

p-value for differences across abuse categories, derived from a likelihood ratio test contrasting nested models with and without the set of abuse covariates