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Data from our group showing RT-induced cognitive deficits. (a) Schematic illustration of the 5-CSRTT apparatus. (b) Fractionated X-ray radiation (4 Gy/d for 5 days) restricted to the frontal cortex of young rats significantly reduced choice accuracy on a 5-CSRTT 6 and 9 months following RT (*P < 0.05). (c) Fractionated WBI in young rats impaired pliancy on a hippocampus-dependent strategy-switching task in the Morris water maze [33] 3-4 weeks following RT (*P < 0.05).
