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. 2013 Jan 17;2:197–203. doi: 10.1016/j.nicl.2013.01.003

Table 3.

Clinical MRI observations.

	49,XXXXY (N = 14)		46,XY (N = 42)
	Count	%	Count	%	χ²	P
Skull deformity
Craniofacial disproportion	2	14	0	0	6.2	.013^a
Plagiocephaly	4	29	1	2	8.9	.003^a^,^b
Dolichocephaly	1	7	0	0	3.1	.081
Thickening of the calvarium	1	7	0	0	3.1	.081
Focal WM signal abnormalities
Exclusively periventricular	1	7	0	0	3.1	.081
Periventricular > subcortical	1	7	0	0	3.1	.081
Subcortical > periventricular	3	21	0	0	9.5	.002^a^,^b
Exclusively subcortical	2	14	1	2	2.9	.087
Colpocephaly	9	64	8	19	10.2	.001^a^,^b
Prominent ventricles	4	29	5	12	2.2	.141
Periventricular cyst(s)	3	21	1	2	5.7	.017^a

^a

Statistically significant.

^b

Survived Bonferroni adjustment.