Table 7.

Cox regression analysis of time from the first employment to the nasal sinus cancer death for the Welsh nickel refiner study

Parameter	Full-cohort	Case-cohort	Generalized Case-cohort
log(AFE − 10)
Est.	2.2091	1.8426	2.1804
S.E	0.4097	0.4405	0.4323
P-value	3.48e – 08	3.44e – 05	4.57e – 07
(YFE − 1915)/10
Est.	0.0768	0.4801	0.0963
S.E	0.2925	0.3824	0.3418
P-value	0.6036	0.209	0.7781
(YFE − 1915)2/100
Est.	−1.2951	−1.2025	−1.4334
S.E	0.5104	0.6846	0.5913
P-value	0.006	0.079	0.0153
log(EXP + 1)
Est.	0.7883	1.1610	0.7654
S.E	0.1629	0.1934	0.1838
P-value	6.519e – 07	1.94e – 09	3.123e – 05