Table 2.

Clinical outcomes in five trials comparing induction chemotherapy regimens in older AML patients. Conventional regimens are shown in gray, comparators in white. Note that early death rates are consistently higher than would be expected from data in the literature on younger AML patients

ADE = daunorubicin + cytarabine + etoposide; Ara-C = cytarabine; COAP = cylophosphamide, vincristine, cytarabine and prednisolone; d = day; DAT = daunorubicin + cytarabine + thioguanine; DNR = daunorubicin; E = etoposide; IA = idarubicin; hr = hour; MA = mitoxantrone; MAC = mitoxantrone + cytarabine; PSC = P-glycoprotein; q = every; TG = thioguanine.