Figure 1. Effect of EHMT2 inhibition on cell proliferation.
LA1-55n (A), IMR-5 (B) and NMB (C) cells were treated with BIX-01294 for 24 h at the concentration of 0.5, 1, 2.5, 5 and 10 μg/ml Proliferation was assessed by trypan blue exclusion to differentiate between dead and live cells. LA1-55n (D), IMR-5 (E) and NMB (F) cells were treated with BIX-01294 for 48 h at the concentration of 0.5, 1, 2.5, 5 and 10 μg/ml. Proliferation was assessed by trypan blue exclusion to differentiate between dead and live cells. * represents a statistical significance (p<0.01) in the difference between the vehicle- and BIX-01294-treated cells.
