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. Author manuscript; available in PMC: 2013 May 9.
Published in final edited form as: J Gene Med. 2009 Sep;11(9):782–790. doi: 10.1002/jgm.1364

Figure 6.

Figure 6

Prior injection of vehicle or insertion of catheter increases transgene expression from subsequently injected pCpG+ [SEAP]. Rats were injected with vehicle (n = 6), inserted with the catheter (n = 8) or received no treatment (n = 6) 2 days prior to injection of 25 µg pCpG+ [SEAP]; during the first injection, any spontaneous CSF outflow was collected (day 0, n = 15). Lumbosacral CSF was also collected 7 and 14 days after the pCpG+ [SEAP] injection and assayed for SEAP. Molar values were calculated assuming a 53-kDa SEAP standard. Data are the mean ± SEM