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. Author manuscript; available in PMC: 2013 May 9.
Published in final edited form as: J Gene Med. 2009 Sep;11(9):782–790. doi: 10.1002/jgm.1364

Table 1.

SEAP concentration (pM) in lumbosacral CSF

Vehicle
(n = 4)		 First injectiona
100 pg of
LPS (n = 4)		 10 ng of
LPS		 10 µg of
LPS (n = 4)
Day 7 Day 7 Day 7 Day 7
20 ± 5 13 ± 6 34 ± 13 (n = 4) 32 ± 16
Day 14 Day 14 Day 14 Day 14
14 ± 6 12 ± 4 17 ± 6 (n = 7) 25 ± 16
Day 92 Day 92 Day 92 Day 92
1.8 ± 0.5 2.7 ± 1.4 2.8 ± 0.7 (n = 7) 1.7 ± 0.6
a

Values in these columns are concentrations of SEAP (pM, mean ± SEM) in lumbosacral CSF at the number of indicated days post-injection of 25 µg of pCpG+[SEAP], which was given 2 days after the first injection. There was no significant difference (p = 0.59, GEE) in expression between the groups. All animals had CCI surgery.