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(A) Zaprinast induces intracellular processing of MSP1 and SERA5. Western blot of schizonts treated as indicated in the additional presence of E64 to prevent egress. (B) Zaprinast treatment of schizonts (in the presence of E64) induces rapid relocalisation of PfAMA1 and loss of PfSUB1. Fixed, permeabilized schizonts were examined by IFA with the antibodies indicated. See also Figure S5 in Text S1.
