Table 1. Detection of CWD in lymphoid follicles.
Codon 96 | DPI | Number of CWD+ follicles | % of affected |
genotype | total follicles | follicles | |
GG | 175 | 0/2547 | 0% |
GS | 175 | 0/2900 | 0% |
GS | 95 | 663/2141 | 31% |
GG | 95 | 1376/1972 | 70% |
SS | 95 | 66/2939 | 2% |
GG | 105 | 828/1635 | 51% |
SS | 105 | 0/2338 | 0% |
SS | 105 | 20/3069 | <1% |
GG | 120 | 1751/2396 | 73% |
GS | 120 | 155/1763 | 9% |
SS | 120 | 168/2061 | 8% |
GG | 175 | 467/2790 | 17% |
GS | 175 | 471/1790 | 26% |
Between 1600 and 3069 lymphoid follicles from head LNs, tonsils, pre-scapular and femoral LNs, Peyer's patches, mesenteric LN, gut LNs and rectum were evaluated in each deer for the presence of CWD by IHC. Percentage of total follicles IHC-positive for CWD ranged between 0->70%, depending on genotype. (*Control mock-infected deer).