Table 1. 2×2 comparison of KRAS mutations frequency in frozen and FFPE tissue sections (n = 159).
KRAS mutation (κ = 0.91, P = 0.96) | ||||||||
Frozen tissues | FFPE tissues | |||||||
AMDS | DS | AMDS | DS | |||||
MT | WT | TOTAL | MT | WT | TOTAL | |||
MT | 31 | 1 | 32 | MT | 21 | 3 | 24 | |
WT | 0 | 57 | 57 | WT | 0 | 45 | 45 | |
TOTAL | 31 | 58 | 89 | TOTAL | 21 | 48 | 69* |
MT = Mutant-type.
WT = Wild type.
κ = κ coefficient.
P = statistical power.
= 1 KRAS analysis in the FFPE tissues were failed in DS due to noisy sequencing data.