Table 1.
| Organ System | Parameters to indicate dysfunction |
|---|---|
| Cardiovascular | Systolic BP <90, elevated lactate, MAP < 70, requiring pressors >2 hours, decrease in systolic BP of >40 |
| Renal | Creatinine increase >0.5 mg/dl, oliguria |
| Neurological | Acute mental status changes |
| Pulmonary | Intubation, BiPAP, supplemental oxygen >6 LPM or 40% face mask, PaO2/FiO2 <300 |
| Hematologic | INR >1.5 or ptt >60 not on anticoagulation, platelets <100 or 50% of baseline |
| Ileus | Decreased bowel motility requiring a change in diet |
| Hepatic | Bilirubin >4 mg/dl and >1.5x baseline |