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. 2013 Apr 15;27(8):853–858. doi: 10.1101/gad.215426.113

Figure 3.

Figure 3.

Evolution of the MRE motif on the D. miranda sex chromosome arms. (A) MSL enrichment at binding sites identified on XL, XR, and the neo-X. The distribution of total MSL binding is plotted on the Y axis versus enrichment level on the X axis for each X chromosome arm. Binding shows a bimodal distribution on XL and XR, with putative CESs defined as those with high MSL occupancy (to the right of the dotted line). (B) Motif searches revealed a conserved 21-bp GA-rich motif, the MRE, within CESs on XL (MEME E-value: 2.1 × 10−343) and XR (MEME E-value: 3.6 × 10−685) and an MRE-like consensus sequence, potentially still evolving, on the neo-X (MEME E-value: 1.1 × 10−152).