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. 2012 Nov 22;34(3):477–488. doi: 10.1007/s10827-012-0431-7

Table 4.

Minimum ChR2 expressions needed to achieve a threshold of 1 mW/mmInline graphic, 20 ms pulse by illuminating some axon parts

  Length [Inline graphicm] Area [Inline graphicm2] ChR2 density [pS/Inline graphicm2] Total ChR [nS]
Unmyelinated AIS 50 200 157 31.4
Unmyelinated axon 400 1278 15 19.2
Myelinated axonInline graphic 400 11.4 1100 12.5
        demyelination
        Inline graphic 1130 12.9
                Inline graphic 1172 13.4
                Inline graphic 1229 14.0
                Inline graphic 1271 14.5
                Inline graphic 1329 15.2

For the myelinated axon, the length of nodes of Ranvier was 1 Inline graphicm, internode distance Inline graphicInline graphicm and Inline graphicF/cmInline graphic

Inline graphicChR2 in nodes only