Table 2. Association of central corneal thickness, curvature and age with corrected and uncorrected intraocular pressure in various populations.
Dataset |
r- square of linear regression analysis (%) |
|||||
---|---|---|---|---|---|---|
Univariate analysis |
Multivariate analysis |
|||||
CCT | R | Age | CCT+R | CCT+Age | CCT+R+Age | |
Europeans n=669 individuals | ||||||
Uncorrected Goldmann IOP | 7.2 | <0.1 | 0.5 | 6.9 | 7.5 | 7.5 |
Corrected IOP | ||||||
Elsheikh equation | 1.1 | 0.2 | 0.1 | 1.2 | 1.2 | 1.3 |
Chihara's equation | 1.5 | 0.1 | 0.4 | 1.6 | 1.9 | 1.98 |
Ehlers equation | 11.2 | 0.2 | 0.1 | 11.3 | 11.5 | 11.5 |
Orrssengo and Pye equation | 2.0 | 0.0 | 0.2 | 2.1 | 2.3 | 2.4 |
Shimmyo's equation | 7.5 | 0.2 | 0.1 | 7.6 | 7.8 | 7.9 |
Indians n=149 individuals | ||||||
Uncorrected Goldmann IOP | 3.6 | 0.3 | <0.1 | 4.6 | 3.8 | 4.7 |
Corrected IOP | ||||||
Elsheikh equation | 0.1 | <0.1 | 0.2 | 0.1 | 0.2 | 0.3 |
Chihara's equation | 0.1 | 0.2 | 0.1 | 0.4 | 0.3 | 0.6 |
Ehlers equation | 10.8 | 2.5 | 0.6 | 11.6 | 10.9 | 11.8 |
Orrssengo and Pye equation | 9.3 | 1.1 | 0.6 | 9.9 | 9.4 | 9.6 |
Shimmyo's equation | 7.2 | 2.3 | 0.5 | 8.2 | 7.3 | 8.3 |
African Americans n=127 individuals | ||||||
Uncorrected Goldmann IOP | 6.6 | Not available | 0.5 | Not available | 6.6 | Not available |
Corrected IOP | ||||||
Elsheikh equation | 1.7 | 1.9 | 3.1 | |||
Chihara's Equation | 1.6 | 0.2 | 1.7 | |||
Ehlers equation | 7.0 | 0.1 | 7.1 | |||
Orrssengo and Pye equation | 1.8 | <0.1 | 1.9 | |||
Shimmyo's equation | 4.5 | <0.1 | 4.6 |
CCT is central corneal thickness in microns; R is mean corneal radius of curvature; age is in years. The r- square of linear regression analysis is given for both univariate and multivariate association of various parameters and IOP represents the amount of variance accounted for. An r-square value of 1.0 is equal to a 100 percent of variance accounted. The statistical significance is evaluated using the regression analysis P-value. The r-square value in bold represents a P value of <0.05, numbers is bold and italics represents a P value of <0.01. The numbers in bold, italics and underlined or bold, italics and double underlined represents P-value of <0.001 or <0.0001 respectively.