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. 2013 Mar 15;27(5):621–629. doi: 10.1038/eye.2013.23

Table 2. Association of central corneal thickness, curvature and age with corrected and uncorrected intraocular pressure in various populations.

Dataset r- square of linear regression analysis (%)
  Univariate analysis
Multivariate analysis
  CCT R Age CCT+R CCT+Age CCT+R+Age
Europeans n=669 individuals
Uncorrected Goldmann IOP 7.2 <0.1 0.5 6.9 7.5 7.5
Corrected IOP
  Elsheikh equation 1.1 0.2 0.1 1.2 1.2 1.3
  Chihara's equation 1.5 0.1 0.4 1.6 1.9 1.98
  Ehlers equation 11.2 0.2 0.1 11.3 11.5 11.5
  Orrssengo and Pye equation 2.0 0.0 0.2 2.1 2.3 2.4
  Shimmyo's equation 7.5 0.2 0.1 7.6 7.8 7.9
             
Indians n=149 individuals
Uncorrected Goldmann IOP 3.6 0.3 <0.1 4.6 3.8 4.7
Corrected IOP
  Elsheikh equation 0.1 <0.1 0.2 0.1 0.2 0.3
  Chihara's equation 0.1 0.2 0.1 0.4 0.3 0.6
  Ehlers equation 10.8 2.5 0.6 11.6 10.9 11.8
  Orrssengo and Pye equation 9.3 1.1 0.6 9.9 9.4 9.6
  Shimmyo's equation 7.2 2.3 0.5 8.2 7.3 8.3
             
African Americans n=127 individuals
Uncorrected Goldmann IOP 6.6 Not available 0.5 Not available 6.6 Not available
Corrected IOP          
  Elsheikh equation 1.7 1.9 3.1      
  Chihara's Equation 1.6 0.2 1.7      
  Ehlers equation 7.0 0.1 7.1      
  Orrssengo and Pye equation 1.8 <0.1 1.9      
  Shimmyo's equation 4.5 <0.1 4.6      

CCT is central corneal thickness in microns; R is mean corneal radius of curvature; age is in years. The r- square of linear regression analysis is given for both univariate and multivariate association of various parameters and IOP represents the amount of variance accounted for. An r-square value of 1.0 is equal to a 100 percent of variance accounted. The statistical significance is evaluated using the regression analysis P-value. The r-square value in bold represents a P value of <0.05, numbers is bold and italics represents a P value of <0.01. The numbers in bold, italics and underlined or bold, italics and double underlined represents P-value of <0.001 or <0.0001 respectively.