Fig. 5.

A, hierarchical cluster analysis of the top 56 discriminatory proteins, showing complete separation of all four control and treatment conditions of the cisplatin-sensitive (KB1P) and -resistant (WEP) tumors. B, expression profiles using spectral counting of the 12 significant proteins with at least eight spectral count differences between the two treated tumor types. Expression profiles were constructed using normalized spectral counts. Lines connect paired samples before and after treatment. Yellow lines represent the three sensitive tumors before and after treatment, and black lines represent the resistant tumors.