Table I. Relationship between CRKL and FLT1 expression and clinicopathological factors in 192 HCC patients.
Characteristics | CRKL expression |
FLT1 expression |
||||
---|---|---|---|---|---|---|
Low |
High |
p valuea | Low |
High |
p valuea | |
(n = 81) | (n = 111) | (n = 81) | (n = 111) | |||
Age | 0.694 | 0.759 | ||||
Years (mean ± S.D.) | 61.19 ± 12.53 | 61.77 ± 11.61 | 61.95 ± 11.15 | 61.21 ± 11.9 | ||
Gender | 0.269 | 0.502 | ||||
Male | 73 | 94 | 72 | 95 | ||
Female | 8 | 17 | 9 | 16 | ||
AFPc | 0.163 | 0.079 | ||||
<400 ng/ml | 68 | 84 | 69 | 83 | ||
≥400 ng/ml | 13 | 27 | 12 | 28 | ||
Stage | 0.432 | 0.432 | ||||
I + II | 59 | 75 | 59 | 75 | ||
III | 22 | 36 | 22 | 36 | ||
Hepatitis B virus | 0.507 | 0.058 | ||||
Negative | 30 | 36 | 34 | 32 | ||
Positive | 51 | 75 | 47 | 79 | ||
Hepatitis C virus | 0.975 | 0.049b | ||||
Negative | 60 | 82 | 54 | 88 | ||
Positive | 21 | 29 | 27 | 23 | ||
Recurrence status | 0.089 | 0.316 | ||||
No | 23 | 20 | 21 | 22 | ||
Yes | 58 | 91 | 60 | 89 | ||
Major vessel invasion | 0.096 | 0.224 | ||||
No | 75 | 94 | 74 | 95 | ||
Yes | 6 | 17 | 7 | 16 |
a p value for age was derived from Student's t test; other p values were derived with a two-tailed Pearson χ2 test. S.D. represents standard deviation.
b p < 0.05.
c AFP represents α-fetoprotein.