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. 2013 Mar 29;288(19):13204–13214. doi: 10.1074/jbc.M113.452177

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© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — Sequence analysis of mAbs against AGEs. A, V region gene usage of the IgM mAbs directed against the AGEs. B, sequence alignment of the hypervariable regions of anti-AGEs mAbs. The completely conserved residues are indicated by an asterisk (*), and the essentially conserved ones are indicated by a period (.) or a colon (:). The sequences were aligned using program ClustalW (version 1.82) and manually modified. The residues are colored according to the standard ClustalX color scheme. The sequences have the following DDBJ accession numbers: ADL7_L, AB793279; DDL17_L, AB793506; ADL19_L, AB793508; ADL19_H, AB793509; BDM1_L, AB793510; BDM1_H, AB793511; BDM2_L, AB793512; BDM2_H, AB793513; BDM3_L, AB793514; and BDM3_H, AB793515.