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. Author manuscript; available in PMC: 2013 May 10.
Published in final edited form as: Am J Physiol Lung Cell Mol Physiol. 2008 Jan 18;294(3):L523–L534. doi: 10.1152/ajplung.00328.2007

Fig. 2.

Fig. 2

NKR subtype-selective agonist effects on inositol phosphate synthesis. Effects of selective NKR agonists [Sar9,Met(O2)11]-substance P (SM-SP; 10 μM) for NK1R (A), [β-Ala8]-neurokinin A(410) (β-ala-NKA; 10 μM) for NK2R (B), and senktide (10 μM) for NK3R (C) on total inositol phosphate synthesis in both native cultured HASM and NKR-transduced cultured HASM (HASM-huNK1R, -huNK2R, -huNK3R) cells. Data are means ± SE, presented as percentages of basal values. *P < 0.05; ***P < 0.001 compared with basal. ###P < 0.001 compared with NKR agonist in native HASM. Numbers in parentheses indicate the number of experiments.