Table 4.

Bleeding complications and postpartum anticoagulation

Parameter	Prophylaxis n=13	Therapeutic n=40
Switched to heparin sodium for delivery (n,%)	(n=12) * 5 (38.5%)	(n=36) ‡ 10 (27.8%)
Time from last injection to delivery (hours, mean ± SD, range)	n = 11 † 48 ± 12 (20–168)	n = 33 † 38 ± 25 (6–144)
Time from delivery until anticoagulation restarted (hours, avg ± SD range)	n = 10 37 ± 42 (12 – 52)	n=35 17 ± 10 (3 – 48)
Postpartum anticoagulation (n, %)	n = 12	n = 39
LMWH alone	0	4 (10%)
LMWH and warfarin	9 (75%)	30 (77%)
LMWH, warfarin, and heparin	1 (8.3%)	2 (5.1%)
None	2 (16.7%)	0
Heparin + warfarin	0	3 (7.7%)
Major Bleeding (n, %)	2 (15.4%)	1 (2.5%)
Minor Bleeding (n, %)	2 (15.4%)	8 (20%)
Bruising (n, %)	4 (30.8%)	22 (55%)
Thromboembolism (n, %)	1 (7.7%)	1 (2.5%)

^*n = 12 since one patient transferred her care to another facility at 28 weeks

^†n = 11, data missing on remaining 2 patients

^‡n = 36 since 2 patients terminated pregnancy, 1 patient had therapy discontinued before delivery and 1 patient lost to follow up