Table 2.

Summary of Linear Regression Analysis for Antenatal Anxiety and 5-HTTLPR Genotype as Predictors of Infant Reactivity at 6 Months

Predictor variables	Antenatal anxiety at 18 weeks				Antenatal anxiety at 32 weeks
B	β	t	p	B	β	t	p
Step 1
Maternal age	−0.014	−0.023	−1.376	.172	−0.019	−0.031	−1.847	.065
Smoking during pregnancy	−0.048	−0.011	−0.635	.526	−0.013	−0.003	−0.178	.859
Alcohol during pregnancy	−0.008	−0.009	−0.553	.581	−0.002	−0.002	−0.12	.904
Maternal education	0.004	0.002	0.098	.922	0.008	0.004	0.215	.830
Household crowding	0.211	0.045	2.716	.007	0.197	0.043	2.625	.009
Gender	0.328	0.060	3.719	.000	0.312	0.057	3.610	.000
Living with partner	−0.366	−0.028	−1.720	.086	−0.46	−0.036	−2.275	.023
Postnatal depression	0.051	0.084	4.246	.000	0.059	0.098	5.272	.000
Step 2
Antenatal anxiety	0.174	0.211	4.151	.000	0.164	0.202	4.091	.000
5-HTTLPR genotype	−0.300	−0.077	−1.532	.126	−0.335	−0.086	−1.747	.081
Step 3
Antenatal anxiety × 5-HTTLPR genotype	−0.050	−0.042	−0.828	.408	0.028	0.024	0.491	.624
5-HTTLPR genotype × gender	0.262	0.105	2.076	.038	0.293	0.117	2.374	.018
Gender × antenatal anxiety	−0.056	−0.106	−2.103	.036	−0.073	−0.141	−2.885	.004
Step 4
Antenatal anxiety × 5-HTTLPR genotype × Gender	0.030	0.040	0.787	.431	0.003	0.004	0.077	.939

Note: N = 3,946, derived from those participants with genetic, prenatal anxiety, and temperament data at 6 months.