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Tumor grade does not correlate with 2-HG concentrations in IDH1 mutant gliomas. Surgically resected glioma tissues were tested by LC–MS for the concentration of 2-HG in confirmed cases of IDH1 mutated gliomas. No significant differences in quantitative 2-HG levels were found due to differences in histology (p < 0.05 by ANOVA test)
