Skip to main content
. Author manuscript; available in PMC: 2013 May 10.
Published in final edited form as: Anesthesiology. 2011 Feb;114(2):363–373. doi: 10.1097/ALN.0b013e3182070c3a

Fig. 1.

Fig. 1

Plasma alanine aminotransferase (ALT, U/L) after renal ischemia–reperfusion injury (IRI). (A) Plasma ALT was measured in C57BL/6 mice exposed to 4 h of pentobarbital (PB) or 1.2% isoflurane (Iso) after sham operation (N = 7 for each group) or renal IRI (N = 8 for each group). (B) Plasma ALT from C57BL/6 mice treated with the sphingosine kinase (SK) inhibitor SKI-II or from SK1 knockout (SK1KO) mice after sham operation (PB anesthesia; N = 4 for each group) or renal IRI (N = 6 for each group) followed by exposure to 4 h of PB or Iso. In all cases (A and B), plasma ALT was measured 24 h after renal IRI. # P less than 0.05 versus. sham mice. * P less than 0.05 versus. PB Renal IRI group. Data presented as mean ± SEM.