Table 3.
Functionally enriched KEGG and Wiki pathway categories related to genes differentially expressed in physically active and sedentary rats immediately following and 2 h post stress.
| Pathway analysis | Gene count | P-value |
|---|---|---|
| FUNCTIONALLY ENRICHED PATHWAY | ||
| KEGG ENRICHMENT ANALYSIS | ||
| Olfactory transduction:04740 | 19 | 2.80en–08 |
| Pathways in cancer:05200 | 8 | 0.0001 |
| Metabolic pathways:01100 | 15 | 0.0001 |
| Allograft rejection:05330 | 4 | 0.0001 |
| MAPK signaling pathway:04010 | 7 | 0.0002 |
| Autoimmune thyroid disease:05320 | 4 | 0.0003 |
| VEGF signaling pathway:04370 | 4 | 0.0004 |
| Intestinal immune network for IgA production:04672 | 3 | 0.0010 |
| C21-Steroid hormone metabolism:00140 | 2 | 0.0014 |
| Graft-vs. host disease:05332 | 3 | 0.0022 |
| WIKI ENRICHMENT ANALYSIS | ||
| Diurnally regulated genes with circadian orthologs:WP1306 | 3 | 0.0006 |
| B cell receptor signaling pathway:WP285 | 4 | 0.0040 |
| Cytokine and inflammatory response:WP271 | 2 | 0.0040 |
| Tryptophan metabolism:WP270 | 2 | 0.0128 |
| Regulation of actin cytoskeleton:WP351 | 3 | 0.0201 |
| TGF beta signaling pathway:WP505 | 2 | 0.0195 |
| MAPK signaling pathway:WP358 | 3 | 0.0238 |
| Kit receptor signaling pathway:WP147 | 2 | 0.0309 |
| IL-5 signaling pathway:WP44 | 2 | 0.0318 |
| GPCRs, class A rhodopsin-like:WP473 | 3 | 0.0564 |