Table 5.
KEGG functionally enriched pathway categories generated from modules of genes correlated to exercise and/or stress.
| Module | Gene count | P-value |
|---|---|---|
| FUNCTIONALLY ENRICHED PATHWAY | ||
| MAGENTA MODULE | ||
| Focal adhesion:04510 | 3 | 0.0014 |
| Type II diabetes mellitus:04930 | 2 | 0.0015 |
| Pancreatic cancer:05212 | 2 | 0.0031 |
| Colorectal cancer:05210 | 2 | 0.0047 |
| Pathways in cancer:05200 | 3 | 0.0061 |
| Neurotropin signaling pathway:04722 | 2 | 0.0099 |
| Insulin signaling pathway:04910 | 2 | 0.0099 |
| Ubiquitin mediated proteolysis:04120 | 2 | 0.0091 |
| Metabolic Pathways:01100 | 2 | 0.3704 |
| TURQUOISE MODULE | ||
| Metabolic Pathways:01100 | 231 | 3.92e–38 |
| Ribosome:03010 | 43 | 7.08e–24 |
| Ubiquitin mediated proteolysis:04120 | 45 | 9.21e–18 |
| Axon guidance:04360 | 42 | 6.30e–15 |
| Huntington's disease:05016 | 56 | 2.63e–13 |
| Alzheimer's disease:05010 | 57 | 7.96e–13 |
| Oxidative phosphorylation:00190 | 43 | 3.01e–12 |
| Regulation of actin cytoskeleton:04810 | 51 | 3.72e–12 |
| Spliceosome:03040 | 37 | 3.89e–12 |
| Cell cycle:04110 | 37 | 5.05e–12 |
| BLACK MODULE | ||
| Cytokine-cytokine receptor interaction:04060 | 4 | 0.0005 |
| Prion Diseases:05020 | 2 | 0.0020 |
| Wnt signaling pathway:04310 | 3 | 0.0023 |
| MAPK signaling pathway:04010 | 4 | 0.0014 |
| Chemokine signaling pathway:04062 | 3 | 0.0039 |
| Toll-like receptor signaling pathway:04620 | 2 | 0.0127 |
| VEGF signaling pathway:04370 | 2 | 0.0087 |
| GnRH signaling pathway:04912 | 2 | 0.0132 |
| Apoptosis:04210 | 2 | 0.0137 |
| Small cell lung cancer:05222 | 2 | 0.0127 |
| BROWN MODULE | ||
| MAPK signaling pathway:04010 | 23 | 3.94e–15 |
| Cytokine-cytokine receptor interaction:04060 | 13 | 9.53e–08 |
| Jak-Stat signaling pathway:04630 | 10 | 2.02e–06 |
| Adipocytokine signaling pathway:04920 | 7 | 4.19e–06 |
| Pathways in cancer:05200 | 14 | 6.26e–06 |
| Hematopoietic cell lineage:04640 | 7 | 1.07e–05 |
| P53 signaling pathway:04115 | 6 | 9.48e–05 |
| Focal adhesion:04510 | 9 | 0.0002 |
| Chronic myeloid leukemia:05220 | 6 | 0.0002 |
| ErbB signaling pathway:04012 | 6 | 0.0002 |