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Mutation frequency of p53 treated with radical cation derived quinones. p53 treated with 250nM B[a]P-7,8-dione is used as a positive control treatment with DMSO is used as a negative control. Data are presented as the percentage of mutation frequency vs the treatment indicated. (A) Dose response with B[a]P-1,6-dione. (B) Dose response using B[a]P-3,6-dione.
