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. 2012 Nov 27;54(3):401–408. doi: 10.1093/jrr/rrs113

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© The Author 2012. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Therapeutic Radiology and Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2. — Kaplan-Meier survival curve of esophageal squamous cell carcinoma (ESCC) patients sub-grouped as miRNA-22 negative or positive. (A) No difference was found between miRNA-22 expression and the overall survival of all 100 ESCC patients. (B) No difference was found between miRNA-22 expression and the overall survival of patients who received only chemotherapy. (C) Significant difference was found between miRNA-22 expression and the overall survival of patients who received concurrent chemotherapy with radiotherapy. The prognosis of miRNA-22 positive cases was significantly longer than that of miRNA-22 negative cases (P = 0.042).