Table 1.
Correlation of patients’ characteristics and changes between preoperative and postoperative Gleason score
| Characteristics | Difference between biopsy and radical prostatectomy Gleason score | p value | ||
|---|---|---|---|---|
|
|
||||
| Equal | Upgrade | Downgrade | ||
|
|
||||
| No. patients, n (%) | 120 (44.3) | 114 (42.1) | 37 (13.7) | |
|
| ||||
| Age (years) | .601† | |||
| Mean ± SD, IQR | 67.0 ± 6.2, 10 | 66.1 ± 6.4, 9 | 66.7 ± 6.5, 9 | |
|
| ||||
| Prostate volume (mL) | .282† | |||
| Mean ± SD, IQR | 44.8 ± 21.3, 29 | 44.2 ± 23.1, 31 | 50.9 ± 24.9, 33 | |
|
| ||||
| PSA (ng/mL) | .693† | |||
| Mean ± SD, IQR | 11.4 ± 9.9, 5.6 | 10.6 ± 5.8, 6.4 | 9.8 ± 6.4, 5.3 | |
|
| ||||
| PSA density (ng/mL2) | .161† | |||
| Mean ± SD, IQR | 0.34 ± 0.43, 0.14 | 0.30 ± 0.23, 0.21 | 0.24 ± 0.21, 0.15 | |
|
| ||||
| No. biopsy cores | .198† | |||
| Mean ± SD, IQR | 12.7 ± 6.6, 9 | 11.4 ± 5.8, 7 | 12.3 ± 4.8, 6 | |
|
| ||||
| Biopsy GS, n (%) | <.001‡* | |||
| ≤6 | 47 (31.1) | 96 (63.6) | 8 (5.3) | |
| ≥7 | 73 (60.8) | 18 (15.0) | 29 (24.2) | |
|
| ||||
| First GS pattern, n (%) | <.001‡* | |||
| ≤3 | 84 (42.0) | 99 (49.5) | 17 (8.5) | |
| ≥4 | 36 (50.7) | 15 (21.1) | 20 (28.2) | |
|
| ||||
| Second GS pattern, n (%) | <.001‡* | |||
| ≤3 | 77 (38.7) | 104 (52.3) | 18 (9.0) | |
| ≥4 | 43 (59.7) | 10 (13.9) | 19 (26.4) | |
|
| ||||
| HGPIN, n (%) | .725‡ | |||
| Positive | 61 (42.1) | 63 (43.4) | 21 (14.5) | |
| Negative | 59 (46.8) | 51 (40.5) | 16 (12.7) | |
|
| ||||
| Prostatitis, n (%) | .922‡ | |||
| Positive | 54 (43.2) | 53 (42.4) | 18 (14.4) | |
| Negative | 66 (45.2) | 61 (41.8) | 19 (13.0) | |
*
statistical significance;
†
Student’s t test;
‡
Mann-Whitney U test;
§
Chi-square χ2 test; SD: standard deviation; IQR: interquartile range; GS: Gleason score; HGPIN: high-grade prostatic intraepithelial neoplasia; PSA: prostate-specific antigen.