Table 3.
Multivariate analysis for NRM, progression/relapse, progression free survival and overall survival (follicular/DLBCL)
| Variables | N | RR (95% CI) | P-value |
|---|---|---|---|
| TRM | |||
| Main effect | |||
| RIC/NST | 202 | 1 | 0.113 |
| Myeloablative | 264 | 1.25 (0.95-1.66) | |
| Histology | |||
| DLBL | 393 | 1 | 0.002 |
| follicular | 73 | 0.52 (0.35-0.79) | |
| Donor type | |||
| Unrelated | 217 | 1 | 0.003 |
| Related | 249 | 0.64 (0.48-0.86) | |
| Progression/relapse | |||
| Main effect | |||
| RIC/NST | 202 | 1 | 0.015 |
| Myeloablative | 264 | 0.66 (0.47-0.92) | |
| Histology | |||
| DLBL | 393 | 1 | 0.002 |
| follicular | 73 | 0.42 (0.25-0.73) | |
| Prior autologous transplant | |||
| No prior auto | 365 | 1 | Poverall=0.006 |
| Prior auto, ≤12 m | 39 | 0.90 (0.49-1.65) | 0.742 |
| Prior auto, >12 m | 62 | 0.30 (0.15-0.63) | 0.001 |
| Contrast:≤12 vs. >12 | 2.99 (1.22-7.35) | 0.017 | |
| Progression free survival | |||
| Main effect | |||
| RIC/NST | 202 | 1 | 0.843 |
| Myeloablative | 264 | 1.02 (0.83-1.27) | |
| Histology | |||
| DLBL | 393 | 1 | <0.001 |
| follicular | 73 | 0.51 (0.37-0.70) | |
| Overall survival | |||
| Main effect | |||
| RIC/NST | 226 | 1 | 0.220 |
| Myeloablative | 307 | 1.14 (0.93-1.40) | |
| Histology | |||
| DLBL | 453 | 1 | <0.001 |
| follicular | 80 | 0.53 (0.39-0.72) |