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. Author manuscript; available in PMC: 2013 May 10.
Published in final edited form as: NMR Biomed. 2011 Aug 31;24(8):943–957. doi: 10.1002/nbm.1772

Figure 5. Comparison of steady state 13C MRS spectra during [2-13C] acetate infusion from a type 1 diabetic with a healthy control subject.

Figure 5

Brain 13C MRS spectra were averaged over the final 45 min of a hypoglycemic period during infusion of [2-13C] acetate. The diabetic subject (top spectrum) had significantly greater labeling in glutamate (Glu) and glutamine (Gln) C4 than the control (bottom spectrum). The acetate C2 signal was also greater in the diabetic subject. Other resonances labeled in the figure include N-acetylaspartate (NAA) C4, GABA C2, and Glu C3.