Table 4. Trends in Medication Use in Patients With HFpEF .
| ACE-I/ ARBs | Aldosterone Antagonists | Aspirin | Beta Blockers | Calcium Channel Blockers | Digoxin | Diuretics | Nitrates | Statins | |
|---|---|---|---|---|---|---|---|---|---|
| Pre-Hospital (%) | |||||||||
| 1995 | 34.7 | N/A | 22.8 | 27.7 | 49.5 | 33.7 | 78.2 | 39.6 | 8.9 |
| 2000 | 38.2 | N/A | 40.8 | 41.2 | 39.0 | 29.2 | 78.7 | 27.0 | 19.5 |
| 2002 | 46.3 | 6.4 | 37.2 | 57.9 | 32.6 | 25.6 | 83.2 | 25.9 | 32.9 |
| 2004 | 52.3 | 6.6 | 45.6 | 62.0 | 33.8 | 22.3 | 81.5 | 21.6 | 40.8 |
| In-Hospital (%) | |||||||||
| 1995 | 45.0 | N/A | 45.0 | 29.8 | 56.7 | 45.0 | 98.8 | 68.4 | 5.3 |
| 2000 | 49.1 | N/A | 57.6 | 51.6 | 45.1 | 35.3 | 97.8 | 59.8 | 20.3 |
| 2002 | 48.2 | 7.5 | 59.4 | 62.4 | 37.6 | 29.6 | 97.6 | 51.1 | 28.1 |
| 2004 | 56.8 | 5.6 | 61.5 | 70.5 | 40.6 | 22.7 | 97.7 | 42.4 | 40.3 |
| Discharge (%) | |||||||||
| 1995 | 36.7 | N/A | 38.0 | 25.3 | 43.0 | 39.9 | 76.0 | 39.2 | 5.1 |
| 2000 | 43.5 | N/A | 47.8 | 44.9 | 35.2 | 27.2 | 74.0 | 25.3 | 20.6 |
| 2002 | 41.7 | 6.4 | 46.2 | 54.9 | 28.1 | 23.7 | 76.9 | 22.0 | 25.9 |
| 2004 | 46.6 | 3.7 | 46.2 | 62.8 | 31.8 | 15.8 | 77.1 | 16.6 | 38.4 |
Pre-hospital data excludes incident cases of acute HF; Hospital discharge data excludes hospital decedents; ACE-I/ARBs = angiotensin converting enzyme inhibitors or angiotensin receptor blockers.