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. 2013 May 10;8(5):e60727. doi: 10.1371/journal.pone.0060727

Table 1. Patient characteristics and demographics by study groups.

Variables Total Non-BC BC P
N = 356 N = 316 (88.8%) N = 40 (11.2%)
Age(year) 48±10 48±9 46±10 0.171
Gender
Male 304 (85.4%) 269 (85.1%) 35 (87.5%) 0.689
Female 52 (14.6%) 47 (14.9%) 5 (12.5%)
Diagnosis
FHF* 45(12.6%) 40(12.7%) 5 (12.5%) 0.577
Cirrhosis 282(79.2%) 250 (79.1%) 32 (80.0%)
Carcinoma 24 (6.7%) 22 (7.0%) 2 (5.0%)
Others 5(1.4%) 4(1.3%) 1(2.5%)
Child-Pugh 0.073
Grade A 117 (32.9%) 113(35.8%) 4 (10.0%)
Grade B 142 (39.9%) 121 (35.4%) 21 (52.5%)
Grade C 97 (27.2%) 82 (26.9%) 15 (37.5%)
ABO blood group
Compatible 306 (86.0%) 272 (86.1%) 34 (85.0%) 0.854
Incompatible 50 (14.0%) 44 (13.9%) 6 (15.0%)
MELD 0.017
MELD≤10 53 (14.9%) 50(15.8%) 3 (7.5%)
11≤MELD≤18 190 (53.4%) 175 (55.4%) 15 (37.5%)
18<MELD≤24 20 (5.6%) 13 (4.1%) 7 (17.5%)
MELD≥25 93 (26.1%) 78 (24.7%) 15 (37.5%)
Surgical factors
WIT* (min) 3.4±0.8 3.4±0.8 3.3±0.8 0.497
CIT* (min) 449±111 440±108 516±107 <0.001
Anhepatic phase (min) 58±10 58±10 58±7 0.578
Operation time (min) 392±95 389±90 411±130 0.851
Blood loss(ml) 3371±3419 3288±3451 4023±3121 0.025
Intravenous infusion(ml) 5890±2852 5893±2881 5869±2646 0.915
Blood products transfusion
RBC(U) 8.3±10.4 8.1±10.6 10.2±8.9 0.013
FFP*(U) 2.0±4.7 1.9±4.4 2.8±6.5 0.86
PLT(U) 0.66±0.96 0.66±0.95 0.65±1.08 0.735
Cryo* (U) 6.3±9.7 5.4±9.0 13.5±12.2 <0.001
Whole blood(U) 0.40±2.07 0.38±2.10 0.55±1.92 0.172
Cell saver(ml) 573±1396 550±1391 754±1439 0.091
Postoperative factors
Immunesuppressor
FK506+MMF 305(85.7%) 270(85.4%) 35(87.5%) 0.595
CysA+MMF 43(12.1%) 38(12.0%) 5(12.5%)
Others 8(2.2%) 8(2.5%) 0(0.0%)
Steroid 195(54.8%) 172(48.3) 23(6.5%) 0.713
Acute rejection 7(2.0%) 6(1.7%) 1(0.3%) 0.569
Chronic rejection 9(2.5%) 6(1.7%) 3(0.8%) 0.068
*

FHF = fulminant hepatic failure; FFP = fresh frozen plasma; WIT = warm ischemia time; CIT = cold ischemia time; Cryo = cryoprecipitate.