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. 2013 May 10;8(5):e60727. doi: 10.1371/journal.pone.0060727

Table 6. Histopathological Features of Liver Biopsies from 37 BC patients.

Features No-cryo Cryo
N = 8 N = 29
Knodell HAI score *
Minimal (1–3) 3 ( 37.5%) 10 (34.5%)
Mild (4–6) 2 (25.0%) 12 (41.4%)
Moderate (7–9) 1 (12.5%) 4 (13.8%)
Marked (10–12) 0 ( 0%) 2 (6.9%)
Hepatic lobule structure
Integrated 7 ( 87.5%) 8 (27.6%)
Disappeared 1 ( 12.5%) 21 (72.4%)
Hepatic cells Vacuolar degeneration 4 ( 50%) 9 (31.0%)
Bile duct
Epithelial hyperplasia 4 ( 50%) 6 (20.7%)
Bile duct disappeared 1 ( 12.5%) 19 (65.5%)
Cholestasis 1 ( 12.5%) 18 (62.1%)
Micro-thrombosis 0 ( 0%) 12 (41.4%)
*

Total of Knodell Histology Activity Index scores for periportal injury, parenchymal injury, and portal inflammation.