Table 6. Histopathological Features of Liver Biopsies from 37 BC patients.
Features | No-cryo | Cryo |
N = 8 | N = 29 | |
Knodell HAI score * | ||
Minimal (1–3) | 3 ( 37.5%) | 10 (34.5%) |
Mild (4–6) | 2 (25.0%) | 12 (41.4%) |
Moderate (7–9) | 1 (12.5%) | 4 (13.8%) |
Marked (10–12) | 0 ( 0%) | 2 (6.9%) |
Hepatic lobule structure | ||
Integrated | 7 ( 87.5%) | 8 (27.6%) |
Disappeared | 1 ( 12.5%) | 21 (72.4%) |
Hepatic cells Vacuolar degeneration | 4 ( 50%) | 9 (31.0%) |
Bile duct | ||
Epithelial hyperplasia | 4 ( 50%) | 6 (20.7%) |
Bile duct disappeared | 1 ( 12.5%) | 19 (65.5%) |
Cholestasis | 1 ( 12.5%) | 18 (62.1%) |
Micro-thrombosis | 0 ( 0%) | 12 (41.4%) |
Total of Knodell Histology Activity Index scores for periportal injury, parenchymal injury, and portal inflammation.