Table 6. Histopathological Features of Liver Biopsies from 37 BC patients.

Features	No-cryo	Cryo
	N = 8	N = 29
Knodell HAI score *
Minimal (1–3)	3 ( 37.5%)	10 (34.5%)
Mild (4–6)	2 (25.0%)	12 (41.4%)
Moderate (7–9)	1 (12.5%)	4 (13.8%)
Marked (10–12)	0 ( 0%)	2 (6.9%)
Hepatic lobule structure
Integrated	7 ( 87.5%)	8 (27.6%)
Disappeared	1 ( 12.5%)	21 (72.4%)
Hepatic cells Vacuolar degeneration	4 ( 50%)	9 (31.0%)
Bile duct
Epithelial hyperplasia	4 ( 50%)	6 (20.7%)
Bile duct disappeared	1 ( 12.5%)	19 (65.5%)
Cholestasis	1 ( 12.5%)	18 (62.1%)
Micro-thrombosis	0 ( 0%)	12 (41.4%)

^*Total of Knodell Histology Activity Index scores for periportal injury, parenchymal injury, and portal inflammation.