Table 1.

Reported cases of squamous cell carcinoma implantation at a PEG tube site

Author	Age	Sex	Site of primary disease	TNM stage	Treatment of primary disease	Timing of PEG placement (before or after primary therapy)	Time from PEG placement to stomal metastasis (months)	Other concurrent treatment failure sites	Treatment of PEG-site metastasis	Length of survival after PEG metastasis diagnosis (months)
Adelson [17]	63	M	Oropharynx	NA	Surgery	Before	6	Lung, liver	Chemo	4
Ananth [3]	55	M	Oral Cavity	T1N2aM0	Surgery + XRT	Before	3.5	NCR	Surgery + Chemo	NED
Balakrishnan [18]	50	M	Larynx	NA	Surgery	Before	NA	NCR	Surgery	NA
Becker [19]	49	M	Hypopharynx	T4N3M0	XRT	Before	3	Lung	Surgery	5
Bhama [20]	51	M	Hypopharynx	T2N1M0	XRT	Before	3.5	Liver, pelvis	Surgery	4
Bushnell [9]	68	M	Supraglottis	T4N2bM0	Surgery + XRT	After	14	Lung	None	18
Chatni [10]	53	F	Hypopharynx	NA	XRT	After	5	Neck	None	NA
Coletti [21]	65	M	Oral Cavity	T4N2cM0	ChemoXRT	Before	9	NCR	ChemoXRT	2
Cossentino [22]	62	M	Oropharynx	T4N2M0	Surgery + XRT	Before	8	Lung	None	2
	66	M	Oropharynx	T3N1M0	XRT	Before	9	NA	None	NA
Cruz [23]	58	M	Oral Cavity	T4N0M0	XRT	Before	5	NA	Surgery + Chemo	4
	48	M	Hypopharynx	T4N3M0	Surgery + ChemoXRT	Before	6	NA	Surgery	4
Daniels [24]	56	M	Oral Cavity	TxN+M0	Surgery + XRT	Before	3	NA	Chemo + Surgery	NA
Douglas [15]	45	M	Oropharynx	T4N3M0	XRT	Before	3.5	NCR	XRT	9
Hawkin [8]	68	M	Oropharynx	T3N0M0	XRT	Before	14	NCR	None	1
Huang [25]	53	M	Oropharynx	T4N2aM0	Surgery + XRT	Before	6	NA	NA	NA
Kurdow [26]	75	F	Hypopharynx	T4N0M0	XRT	Before	4	NA	NA	NA
Laccourreye [11]	65	M	Hypopharynx	T3N0M0	ChemoXRT	After	11	Liver	XRT	4
Lee [27]	41	M	Oropharynx	T4N2bM0	Surgery + ChemoXRT	Before	13	Liver, spleen	None	1
Lim [28]	51	M	Oropharynx	T4N1M0	Surgery + XRT	Before	8	Lung	Surgery	NA
Lin [13]	56	M	Oropharynx	T4N0M0	Surgery + XRT	Before	5	NCR	NA	2
Maccabee [29]	63	F	Hypopharynx	T4N1M0	ChemoXRT	Before	5	Primary site	None	3
Meurer [30]	45	M	Oropharynx	T3N1M0	Surgery	Before	12	Lung	ChemoXRT	17
	76	F	Oropharynx	T2N0M0	XRT	Before	13	Lung	Surgery	16
Mincheff [4]	59	M	Oropharynx	T4N2bM0	Surgery + XRT	NA	4	NCR	Surgery + XRT	NA (Hospice)
Potochny [31]	44	M	Hypopharynx	T2N2M0	Surgery + XRT	Before	9	NCR	Surgery	NED
Preyer [14]	72	M	Oropharynx	T4N2cM0	ChemoXRT	Before	3	Lung	None	3
Purandare [32]	50	F	Oropharynx	T3N2M0	Surgery	NA	9	Primary site, neck	NA	NA
	62	M	Oral Cavity	T2N0M0	Surgery	NA	15	Primary site	NA	NA
Schiano [12]	43	M	Hypopharynx	T4NxM0	Chemo	After	4	Primary site, neck	NA	NA
Schneider [33]	61	F	Oropharynx	T4N0M0	Surgery + XRT	Before	10	NCR	Surgery	NED
Sharma [34]	40	M	Oral Cavity	T4N3M0	ChemoXRT	Before	6	Primary site	Surgery + Chemo	NA (Hospice)
Siddiqi [35]	56	F	Supraglottis	T3N2bM0	ChemoXRT	Before	7	NA	NA	2
Sinclair [36]	61	M	Oropharynx	T2N1M0	XRT	Before	5	Left axilla	Surgery + ChemoXRT	NA (recurrent disease detected)
Thakore [37]	50	M	Larynx	NA	Surgery + ChemoXRT	NA	NA	Lung, hip, brain	ChemoXRT	6
Thorburn [38]	56	M	Supraglottis	T4N3M0	XRT	Before	11	NA	NA	1
Tucker [16]	NA	NA	Hypopharynx	NA	ChemoXRT	Before	3	NA	NA	NA
Van erpecum [39]	69	M	Hypopharynx	T4N0M0	XRT	Before	10	NCR	XRT + Surgery	1
Current series	69	M	Hypopharynx	T2N2aM0	ChemoXRT	Before	22	Adrenals, liver, lung	Chemo XRT	8
	77	M	Supraglottis	T3N1M0	ChemoXRT	Before	16	NCR	Chemo	5
	46	M	Oral Cavity	T4N1M0	ChemoXRT	Before	8	NCR	Surgery	19
	64	M	Oropharynx	T1N2cM0	XRT	Before	7	Primary site, neck	Surgery	NED
Total cases	42

Abbreviations: NA, not available; Chemo, Chemotherapy; XRT, radiation therapy; NCR, no concurrent recurrence; NED, no evidence of disease.