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. 2013 May 10;8(5):e64402. doi: 10.1371/journal.pone.0064402

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© 2013 Ma et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The first two PCs of the PCA of 31,991 expressed transcripts describe 32.1% of the dataset variance. The five-day RPM samples showed a separation from 1 g controls and seven-day RPM samples in PC #1 (22.5% of the variance). (B) K-mean clustering of the 1625 significantly regulated probes. The color scale represents upregulation (red) or downregulation (blue) of probes. Outliers are marked in orange (upregulated) or green (downregulated). (C–H) STRING visualization of known and predicted physical and functional interactions between the proteins organized in cluster 1 (C), clusters 2, 7 and 9 (D), clusters 3 and 5 (E), cluster 4 (F), cluster 6 (G) and cluster 8 (H).