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. 2013 Mar 19;42(1):23. doi: 10.1186/1916-0216-42-23

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Copyright © 2013 Lin et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Examples of a case from Group 1 (favourable outcome group; upper panel, A, B, C) and a case from Group 2 (adverse outcome group; lower panel, D, E, F). A (diffuse punctate signals) and D (negative) showing CISH staining of HPV-HR DNA; B (diffuse strong cytoplasmic staining and nuclear staining) and E (negative) showing IHC staining of p16 protein; C (negative) and F (diffuse strong nuclear staining) showing IHC staining of cyclin D1. (Original magnification 100×).