Table 3.

Geometric mean percent adult emergence, predicted adult emergence and percent efficacy relative to non-treated controls for predicted adult flea emergence from eggs collected from cats treated with a 19.5% w/v indoxacarb topical spot-on

	Non-treated controls1,2		Indoxacarb1,2
Study day3	% Adult emergence4	Predicted emergence5	% Adult emergence4	Predicted emergence5	Efficacy6
1	50.1a	327.9	4.6 b	10.2	96.9
2	46.1a	289.6	0.0b	0.0	100.0
3	67.0a	395.2	0.0b	0.0	100.0
9	77.1	501.8	NE	0.0	100.0
10	79.8	763.7	NE	0.0	100.0
16	75.3	345.5	NE	0.0	100.0
17	76.4	524.2	NE	0.0	100.0
23	84.3	623.2	NE	0.0	100.0
24	83.6	908.2	NE	0.0	100.0
30	77.0	436.2	NE	0.0	100.0
31	85.2a	604.0	0.0b	0.0	100.0
37	75.4a	370.2	20.0b	0.1	99.9
38	63.7a	388.6	0.0b	0.0	100.0
44	77.3a	177.5	66.1a	6.4	96.4
45	82.3a	418.1	62.5a	4.3	99.0

¹ Each of 8 cats in the control group received no treatment. Each of 8 cats in the 19.5% w/v indoxacarb group were administered the topical spot-on according to label directions on Day 0.

² Each cat was infested with 50 adult Ctenocephalides felis from the KS1 strain on days -2, 7, 14, 21, 28, 35 & 42.

³ Days post-treatment that eggs were collected.

⁴ % Adult emergence = (# of adults emerging/# of eggs collected) × 100.

⁵ Predicted emergence = (% emergence × geometric mean # eggs collected from Table 2).

⁶ % Efficacy = ((predicted adult emergence control-predicted adult emergence treatment)/geometric mean % adult emergence control) × 100.

NE = no flea eggs collected.

^a,.b Values across rows with unlike superscripts are significantly different (P < 0.05).