Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Evolution of the type I error of the Wald test according to the study design. Assuming ϵA = ϵB = 0.999, no limit of detection (“All data”, red line) or a limit of detection at 12 IU/mL (“ML”, blue line). N: number of patients per group of treatment; n: number of viral load measurements per patient; ntot: total numbers of observations per group of treatment.
